Исследования

MicrocynAH® исследованная, протестированная, безопасная и эффективная серия продуктов для животных на рынке, которая содержит хлорноватистую кислоту.

Ниже Вы найдете исследования и статьи по запатентованной технологии Microcyn®.

Note: Microcyn, Dermacyn, Oxum, Super-Oxidized Solution (SOS) are trademarks of Sonoma Pharmaceuticals Inc.

1. Why aren’t you using Microcyn Solution? Assistant Professor of Surgery, Harvard Medical School, Boston, MA Chief, Division of Podiatric Surgery, Cambridge Health Alliance, Cambridge, MA Research Director, California School of Podiatric Medicine at SMU, Oakland, CA. *(Microcyn files: p. 1-32).

2. In vivo characterization of Microcyn™ effects on early phase of allergic reactions using a murine model of passive cutaneous anaphyaxis. April 9th, 2008. Elizabeth Sanchez- Miranda, Gonzalez, D., Gutierrez, AA., Gonzalez-Espinosa, C. * (Microcyn files: p. 33-44).

3. Wound Healing in Chronic Lower Extremity Wounds Comparing Super-Oxidized Solution (SOS) vs. Saline. DFCON Poster 2008. Robert G. Frykberg, DPM, MPH; Arthur Tallis, DPM; Edward Tierney, DPM; Carl T. Hayden. *(Microcyn files: p. 45-46).

4. Dermacyn® Effective in Treatment of Chronic Wounds with Extensive Bioburden while Reducing Local Pain Levels. POSTER - SAWC 07. Debra J. Peterson, CCRN, MSN, ACNP-BC; Karre Hermann, MSN, APNP-BC; Jeffrey A. Niezgoda MD, FACEP, FACHM. *(Microcyn files: p. 47-48).

5. Dermacyn, A Novel Superoxidized Solution Facilitates Wound Healing: Early Experience in Leg Wounds and Limb Salvage. POSTER - SAWC 06. David E. Allie, MD; Chris J Hebert, RT, R-CIS, Mitchell D Lirtzman, MD; Charles H Wyatt, MD; V Antoine Keller, MD; Adam A Allie, MS; Craig M Walker, MD. *(Microcyn files: p. 49-50).

6. Persistent Improvement of Diabetic Foot Ulcer Perfusion Results From Application of Superoxidized Water. Tcpo2 08.24.08.PPT. Cheryl M. Bongiovanni, PhD,  RVT, CWS Lake District Hospital, Lakeview, OR. *(Microcyn files: p. 51-60).

7. Hypochlorous Acid: An Ideal Wound Care Agent With Powerful Microbicidal, Antibiofilm, and Wound Healing Potency. WOUNDS 2014; 26(12): 342-350. Serhan Sakarya, MD; Necati Gunay, MS; Meltem Karakulak, MS; Barcin Ozturk, MD; Bulent Ertugrul, MD. *(Microcyn files: p. 61-70).

8. Super-Oxidized Solution (Dermacyn Wound Care) as Adjuvant Treatment in the Postoperative Management of Complicated Diabetic Foot Osteomyelitis: Preliminary Experience in a Specialized Department. International Journal of Lower Extremity Wounds, pub. online 26 Feb., 2013. Javier Aragón-Sánchez, Jose L. Lázaro-Martínez, Yurena Quintana-Marrero, Irene Sanz-Corbalán, Maria J. Hernández-Herrero, Juan J. Cabrera-Galván. *(Microcyn files: p. 71-80).

9. Neutral super-oxidised solutions are effective in killing P. aeruginosa biofilms. Biofouling Vol. 25, No. 1, January 2009, 45–54. Karin Sauer, Eileen Thatcher, Robert Northey, Andres A. Gutierreza. *(Microcyn files: p. 81-90).

10. An Open-label, Three-arm Pilot Study of the Safety and Efficacy of Topical Microcyn Rx Wound Care versus Oral Levofloxacin versus Combined Therapy for Mild Diabetic Foot Infections. J Am Podiatr Med Assoc 101(6): 484-496, 201. Adam Landsman, DPM, PhD; Peter A. Blume, DPM; Douglas A. Jordan, Jr., DPM; Dean Vayser, DPM; Andres Gutierrez, MD, PhD. *(Microcyn files: p. 91-104).

11. Diabetic Foot Management - Role of Superoxidised Solution. Dr. Amar P. S. Suri MBBS, CPP (Podiatry) Beth Israel Hospital, Harvard, USA Diabetic Foot Fellowship-Temple Uni, USA Diabetic Footcare Center, New Delhi, India. *(Microcyn files: p. 105-162).

12. Sterilant for Human Wounds is Changing Patients’ Lives. Infection Control Today, November 2004 Vol. 8, No. 11. Fermin Martinez, MD. *(Microcyn files: p. 163-166).

13. Efficacy and safety of neutral pH superoxidised solution in severe diabetic foot infections. Int Wound J 2007;4:353–362. Fermín R Martínez-De Jesús, Antonio Ramos-De la Medina, José María Remes-Troche, David G Armstrong, Stephanie C Wu, Jose Luis Lázaro Martínez, Juan V Beneit-Montesinos. *(Microcyn files: p. 167-176).

14. Methicilin-resistent Staphylococcus aureus problem in health care. ABSTRACT - STUTTGART 05 - F-04-01-08. L.Veverkova, V.Jedlicka, M.Vesely, R.Tejkalova, S.Zabranska, I.Capov, M.Votava. *(Microcyn files: p. 177-178).

15. Advanced Wound Care with Stable, Super-Oxidized Water. A look at how combination therapy can optimize wound healing. Supplement to January Wounds, 2006. Tom A. Wolvos, MD, FACS. *(Microcyn files: p. 179-182).

16. Reducing Bacterial Infectious Complications from Burn Wounds. Supplement to January Wounds, 2006. A look at the use of Oculus Microcyn60 to treat wounds in Mexico. Ariel Miranda Altamirano, MD. *(Microcyn files: p. 183-186).

17. A cytotoxic analysis of antiseptic medication on skin substitutes and autograft. British Journal of Dermatology 2007. Q. le Duc, M. Breetveld, E. Middelkoop, R.J. Scheper, M.M.W. Ulrich, S. Gibbs. *(Microcyn files: p. 187-194).

18. The Science Behind Stable, Super-Oxidized Water. Exploring the various applications of super-oxidized solutions. Supplement to January Wounds, 2006. Andrés A. Gutiérrez, MD, PhD. *(Microcyn files: p. 195-198).

19. Use of Dermacyn a new antiseptic agent for the local treatment of diabetic foot ulcers. ABSTRACT - STUTTGART 05. L.Dalla Paola, E.Brocco, A.Senesi, S.Ninkovic, M.Merico, D.De Vido. *(Microcyn files: p. 199-200).

20. Treating Diabetic Foot Ulcers with Super-Oxidized Water. A look at advances in this pH-neutral, non-toxic treatment. Supplement to January Wounds, 2006. Luca Dalla Paola, MD. *(Microcyn files: p. 201-204).

21. A Randomized Controlled Trial to Examine the Efficacy and Safety of a New Super-Oxididized Solution for the Management of Wide Postsurgical Lesions of the Diabetic Foot. The International Journal of Lower Extremity Wounds 9(1)10-15, 2010. A.Piaggesi, MD; C.Goretti, MD; S.Mazzurco, DPM; C.Tascini, MD; A.Leonildi, PhD, L.Rizzo, MD, A.Tedeschi, MD; G.Gemignani, MD; F.Menichetti, MD; S.Del Prato, MD, PhD. *(Microcyn files: p. 205-210).

22. Activity of a pH Neutral Super-Oxidized Solution Against Bacteria Selected for Sodium Hypochlorite Resistance. J.Dardine, L.Diaz, C.Martinez, E.Thatcher. *(Microcyn files: p. 211-212).

23. The Anti-Viral Efficacy of a New Super-Oxidized Solution. M.Taketa-Graham, A.A.Gutierrez, E.Thatcher. *(Microcyn files: p. 213-214).

24. The Effectiveness of Neutral pH, Super-oxidized Solution for the Treatment of Infected Diabetic Foot Wounds. Suri abstract DFCon 03.14.08. *(Microcyn files: p. 215-216).

25. Clinical results about an antimicrobial solution (Dermacyn® Wound Care) in the treatment of infected chronic wounds. E.Ricci, S.Astolfi, R.Cassino. *(Microcyn files: p. 217-218).

26. Clinical Outcomes of Wide Postsurgical Lesions in the Infected Diabetic Foot Managed With 2 Different Local Treatment Regimes Compared Using a Quasi-Experimental Study Design: A Preliminary Communication. Lower Extremity WOUNDS 6(1); 2007 pp. 22-27. Chiara Goretti, Sabrina Mazzurco, Laura Ambrosini Nobili, Silvia Macchiarini, Anna Tedeschi, Francesca Palumbo, Alessia Scatena, Loredana Rizzo, Alberto Piaggesi. *(Microcyn files: p. 219-224).

27. Efficacy and Safety of a Novel Super-Oxidized Solution in the Management of Wide Post-Chirurgical Lesion in the Infected Diabetic Foot. Chiara Goretti, Sabrina Mazzurco, Laura Ambrosini, Silvia Macchiarini, Anna Tedeschi, Francesca Palumbo, Alessia Scatena, Loredana Rizzo, Alberto Piaggesi. *(Microcyn files: p. 225-226).

28. Treating Infected Diabetic Wounds With Superoxidizes Water As Anti-septic Agent: A Premilinary Experience. Accepted June 26, 2007. Syed Fazle Hadi, Tanwir Khaliq, Nighat Bilal, Imran Sikandar, Muhammad Saaiq, Muhammad Zubair, Sidra Aurangzeb. *(Microcyn files: p. 227-230).

29. Treatment of Diabetic Foot Ulcer: An Overview Strategies for Clinical Approach. Current Diabetes Reviews, 2006, 2, 431-447. Luca Dalla Paola, Ezio Faglia. *(Microcyn files: p. 231-248).

30. Comparative Efficacy and Tolerability of Oxum against Povidone Iodine Topical Application in the Post-caesarean Section Wound Management. Indian Medical Gazette, December 2007. Ashok Anand. *(Microcyn files: p. 249-256).

31. Comparative Efficacy and Tolerability of Microcyn Superoxidized Solution (Oxum) against Povidone Iodine Application in Orodental Infections. Indian Medical Gazette, February 2008. Hemant Dhusia, Professor. *(Microcyn files: p. 257-264).

32. Treatment of Staphylococcus aureus colonization in atopic dermatitis decreases disease severity. Pediatrics. 2009 May;123(5):e808-14. doi:10.1542/peds.2008-2217. Huang JT., Abrams M., Tlougan B., Rademaker A., Paller AS. *(Microcyn files: p. 265-266).

33. Super-Oxidized Solution (SOS) Therapy for Diabetic Foot Ulcers. Fernando Uribe M.D. Prof. *(Microcyn files: p. 267-268).

34. Super-oxidized solution inhibits IgE-antigen-induced degranulation and cytokine release in mast cells. International Immunopharmacology 7/2007, 1013–1024. J. Medina-Tamayo, E. Sánchez-Miranda, H. Balleza-Tapia, X. Ambriz, M.E. Cid, D. González-Espinosa, A.A. Gutiérrez, C. González-Espinosa. *(Microcyn files: p. 269-280).

35. Emerging Innovations In Treatment. Podiatry Today, September 11, 2006. Brian McCurdy, Senior Editor. *(Microcyn files: p. 281-288).

36. Microcyn™: a novel super-oxidized water with neutral pH and disinfectant activity. Received 30 August 2004; accepted 19 April 2005. C. Landa-Solis, D. González-Espinosa, B. Guzmán-Soriano, M. Snyder, G. Reyes-Terán, K. Torres, A.A. Gutierrez. *(Microcyn files: p. 289-298).

37. Antipuric Hydrogel for the Treatment of Atopic Dermatitis: An Open-Label Pilot Study.  Cutis 2012;90:97-102. Zoe Diana Draelos, MD. *(Microcyn files: p. 299-304).

38. Effects of pH-neutral, super-oxidised solution on human dermal fibroblasts in vitro. Int Wound J 2007;4:241–250. Diana González-Espinosa, Leafar Pérez-Romano, Beatriz Guzmán-Soriano, Edmundo Arias, Cheryl M Bongiovanni, Andrés A Gutiérrez. *(Microcyn files: p. 305-314).

39. Clinical Experience with a New, Stable, Super-Oxidized Water in Wound Treatment. WOUNDS, January 2006. *(Microcyn files: p. 315-320).

40. Nonsurgical Management of Chronic Wounds in Patients With Diabetes. The Journal for Vascular Ultrasound 30(4): 215–218, 2006. Cheryl M. Bongiovanni, PhD, RVT, CWS. *(Microcyn files: p. 321-324).

41. Superoxidized Water Improves Wound Care Outcomes in Diabetic Patients. Diabetic Microvascular Complications Today, May/June 2006. Cheryl M. Bongiovanni, PHD. *(Microcyn files: p. 325-328).

42. Super-Oxidized Solution (SOS) Therapy for Infected Diabetic Foot Ulcers. WOUNDS 2006;18(19):262-270, 2006. Luca Dalla Paola, MD; Enrico Brocco, MD; Antonella Senesi, MD, PhD; Maurizio Merico, MD; Daniele De Vido, MD; Roberta Assaloni, MD; Roberto DaRos, MD. *(Microcyn files: p. 329-338).

43. U.S. Phase II Clinical Trial Results. Adam Landsman, DPM; PhD, FACFAS; Beth Israel Deaconess Medical Center Boston, MA. Efficacy and Safety of Microcyn Technology in Managing Post-Surgical Lesions of the Infected Diabetic Foot. Alberto Piaggesi, MD, Diabetic Foot Section, Department of Endocrinology and Metabolism, Universitá di Pisa Azienda Ospedaliera Pisana. DiabeticFoot Management - Role of Microcyn. Dr. Amar P.S. Suri, MBBS, CPP (Podiatry), Beth Israel Hospital, Harvard, USA; Diabetic Foot Fellowship-Temple Uni, USA; Diabetic Footcare Center, New Delhi, India. Oculus Innovative Sciences, Inc. DFCon 08 Webcast Hollywood, California March 14 2008. *(Microcyn files: p. 339-360).

44. Antibacterial Activity of Microcyn Gel Formulation, containing Hypochlorous Acid. Winter Clinical Dermatology Conference, HI 2016. MicroMed Laboratories, Joseph Fowler, MD. *(Microcyn files: p. 361-362).

45. The role of super oxidized solution in the management of diabetic foot ulcer: Our experience. Nepal Med. Coll. Journal, 2007. Ravi Kumar Chittoria, Mutheeswaraiah Yootla, Leela Mohan Chandra Sekhara Rao Sampatrao, S. Venkat Raman. *(Microcyn files: p. 363-368).

46. Efficacy and Safety of Oxum in Treatment of the Venous Ulcer. Dharap SB, Ghag GS, Kulkarni KP, Venkatesh V.  J Indian Med Assoc. 2008;106(5):326–330. *(Microcyn files: p. 369-374).

47. Dermacyn Irrigation in Reducing Infection of a Median Sternotomy Wound. Heart Surg Forum. 2010;13(4):E228–E232. Mohd AR, Ghani MK, Awang RR, Su Min JO, Dimon MZ. *(Microcyn files: p. 375-380).

48. The clinical efficacy of Dermacyn on deep partial thickness burn wounds. Department of Burn, Jishuitan Hospital, Beijing, 2008. Ning Fanggang, Zhang Guoan. *(Microcyn files: p. 381-386).

49. Treatment of 2nd & 3rd Degree Burns in 48 Pediatric Patients Without Routine Antibiotics using New “Super-oxidized Water Technology” Microcyn™. ABSTRACT 2005. Rudolfo Ariel Miranda-Altamirano M.D., David Medina-Preciado M.D., Antonio Mena-Flores M.D., Barnett L. Cline, M.D., Don Charles Wukasch M.D. *(Microcyn files: p. 387-388).

50. A Prospective, Randomized, Single-Blind, Clinical Investigation of a Neutral pH Superoxidized Water in Patients with Infected Diabetic Foot Ulcers. CLINICAL STUDY REPORT, FINAL: 25 June 2004. Dr. Fermin Rafael Martinez-De Jesus. *(Microcyn files: p. 389-412).

51. Super-Oxidized Solution (SOS) irrigation in Root Canal Treatment. Miguel Angel Flores-Martínez. Universidad Michoacana de San Nicolás de Hidalgo, U.M.S.N.H. Morelia Michoacán, México, 2005. *(Microcyn files: p. 413-418).

52. Dermacyn as the Local Treatment for Infected Diabetic Foot Wounds – a case series. B.T.Monaghan Podiatry Services Manager and Clinical Lead in Diabetes Belfast City Hospital - Belfast Health and Social Care Trust, J.H.Cundell Lecturer Practioner, University of Ulster/ Belfast City Hospital - Belfast Health and Social Care Trust, 2007. *(Microcyn files: p. 419-420).

53. The Anti-Bacterial Efficacy of a New Super-Oxidized Solution. Thatcher E., Gutierrez AA, 2007. *(Microcyn files: p. 421-422).

54. Expert Recommendations for the Use of Hypochlorous Solution: Science and Clinical Application. Ostomy Wound Management, May 2015. David G. Armstrong, Gregory Bohn, Paul Glat, Steven J. Kavros, Robert Kirsner, Robert Snyder, William Tettelbach.  
Note. Sponsored and guided by Innovacyn Inc. containing no evaluation of company´s own HOCl-products. Table 4. - Microcyn Rx, Microcyn-60, Microcyn, Dermacyn & Oxum (12 products of 15) are trademarks of Sonoma Pharmaceuticals Inc. (existing name). *(Microcyn files: p. 423-442).

55. Anti-inflammatory effects of an oxychlorine compound in a murine model of passive cutaneous anaphylaxis. Elizabeth Sanchez-Miranda, Diana Gonzalez-Espinosa, Andres A. Gutierrez, Claudia Gonzalez-Espinosa. 2008. *(Microcyn files: p. 443-444).

56. Efficacy and Compatibility of Combination Therapy with Super-Oxidized Solution* and a Skin Substitute for Lower Extremity Wounds. Regulski M., Floros R., Petranto R., Migliori V., Alster H., Pfeiffer D. 2008. *(Microcyn files: p. 445-446).


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